000 nam a22 7a 4500
999 _c31063
_d31063
008 220511b xxu||||| |||| 00| 0 eng d
020 _a9781138048980
082 _a610.727
_bPRA
100 _aPradhan, Vivek
245 _aConfidence intervals in clinical research
260 _aChapman & Hall/CRC,
_b2021
_cBoca Raton :
300 _axiv, 226 p.,
_bill.,
_c24 cm
365 _b00
_cGRATIS
_d00
490 _aChapman & Hall/CRC Biostatistics Series
504 _aIncludes bibliographical references and index.
520 _aConfidence Intervals for Discrete Data in Clinical Research is designed as a toolbox for biomedical researchers. Analysis of discrete data is one of the most used yet vexing areas in clinical research. The array of methodologies available in the literature to address the inferential questions for binomial and multinomial data can be a double-edged sword. On the one hand, these methods open a rich avenue of exploration of data; on the other, the wide-ranging and competing methodologies potentially lead to conflicting inferences, adding to researchers' confusion and frustration and also leading to reporting bias. This book addresses the problems that many practitioners experience in choosing and implementing fit for purpose data analysis methods to answer critical inferential questions for binomial and count data. The book is an outgrowth of the authors' collective experience in biomedical research and provides an excellent overview of inferential questions of interest for binomial proportions and rates based on count data, and reviews various solutions to these problems available in the literature. Each chapter discusses the strengths and weaknesses of the methods and suggests practical recommendations. The book's primary focus is on applications in clinical research, and the goal is to provide direct benefit to the users involved in the biomedical field.
650 _aMedicine
650 _aResearch
650 _aBiology
650 _aAgresti and Min interval
650 _aMOVER intervals
650 _aBayesian
650 _aChan and Zhang's (CZ) interval
650 _aJeffreys intervals
650 _a Katz interval
650 _aMarkov Chain Monte Carlo (MCMC) methods
650 _aScore interval
650 _aConfidence interval
650 _aSAS/R code
700 _aMenon, Sandeep M.
700 _aGangopadhyay, Ashis
700 _aBasu, Cynthia
700 _aBanerjee, Tathagata
942 _2ddc
_cBK